2015

PRMT1 and PRMT8 regulate retinoic acid dependent neuronal differentiation with implication to neuropathology
Simandi, Z., Czipa, E., Horvath, A., Koszeghy, A., Bordas, C., Poliska, S., Juhasz, I., Imre, L., Szabo, G., Dezso, B., Barta, E., Sauer, S., Karolyi, K., Kovacs, I., Hutoczky, G., Bognar, L., Klekner, A., Szucs, P., Balint, B.L., Nagy, L.
Stem Cells
33 (3) pp. 726-741. (2015)

Combination of IgG N-glycomics and corresponding transcriptomics data to identify anti-TNF-α treatment responders in inflammatory diseases
Varadi, C., Hollo, Z., Poliska, S., Nagy, L., Szekanecz, Z., Vancsa, A., Palatka, K., Guttman, A.
Electrophoresis 36:(11-12) pp. 1330-1335. (2015)

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice
Ruhl, R., Krzyżosiak, A., Niewiadomska-Cimicka, A., Rochel, N., Szeles, L., Vaz, B., Wietrzych-Schindler, M., Alvarez, S., Szklenar, M., Nagy, L., de Lera, A.R., Krężel, W.
PLOS Genetics
11: (6) Paper e1005213. (2015)

Differentiation of Adipocytes in Monolayer from Mouse Embryonic Stem Cells
Cuaranta-Monroy, I., Simandi, Z., Nagy, L.
Methods in Molecular Biology, Embryonic Stem Cell Protocols 1341: pp. 407-415. (2015)

A6.15 Genetic signatures may be associated with vascular pathology in rheumatoid arthritis
Poliska, S., Vegh, E., Vancsa, A., Bodnar, N., Szamosi, S., Csumita, M., Kerekes, G., Szabo, Z., Szucs, G., Szanto, S., Zahuczky, G., Soltesz, P., Nagy, L., Szekanecz, Z.
Annals of the Rheumatic Diseases 74: (1) paper A61. (2015)

Genomewide effects of peroxisome proliferator-activated receptor gamma in macrophages and dendritic cells – revealing complexity through systems biology
Cuaranta-Monroy, I., Kiss, I., Simandi, Z., Nagy, L.
European Journal Of Clinical Investigation 45:(9) pp. 964-975. (2015)

2014

Mapping the genomic binding sites of the activated retinoid x receptor in murine bone marrow-derived macrophages using chromatin immunoprecipitation sequencing.
Daniel, B., Balint, B.L., Nagy, Z., Nagy, L.
Methods in Molecular Biology 1204: pp. 15-24. (2014)

PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors
Kotlinowski, J., Grochot-Przeczek, A., Taha, H., Kozakowska, M., Pilecki, B., Skrzypek, K., Bartelik, A., Derlacz, R., Horrevoets, A.J.G., Pap, A., Nagy, L., Dulak, J., Jozkowicz, A.
Cardiovasular Diabetology
13: pp. 150. (2014)

Measuring expression levels of small regulatory RNA molecules from body fluids and formalin-fixed, paraffin-embedded samples
Gyongyosi, A., Docs, O., Czimmerer, Z., Orosz, L., Horvath, A., Torok, O., Mehes, G., Nagy, L., Balint, B.L.
Methods In Molecular Biology 1182: pp. 105-119. (2014)

Brazda, P., Krieger, J., Daniel, B., Jonas, D., Szekeres, T., Langowski, J., Toth, K., Nagy, L., Vamosi, G.
Ligand binding shifts highly mobile RXR to chromatin-bound state in a coactivator-dependent manner as revealed by single cell imaging.
Molecular and Cellular Biology 34:(7) pp. 1234-1245. (2014)

Cuaranta-Monroy, I., Simandi, Z., Kolostyak, Z., Doan Xuan Quang Minh, Poliska, S., Bacso, Z., Nagy, L.
Highly efficient differentiation of embryonic stem cells into adipocytes by ascorbic acid
Stem Cell Research 13: pp. 88-97. (2014)

Daniel, B., Nagy, G., Hah, H., Horvath, A., Czimmerer, Z., Poliska, S., Gyuris, T., Keirsse, J., Gysemans, C., Ginderachter, J., Balint, B. L., Evans, R. M., Barta, E., Nagy, L.
The Active Enhancer Network Operated by Liganded RXR Supports Angiogenic Activity in Macrophages
Genes & Development 28:(14) pp. 1562-1577. (2014)

Daniel, B., Nagy, G., Nagy, L.
The intriguing complexities of mammalian gene regulation: How to link enhancers to regulated genes. Are we there yet?
FEBS Letters 588:(15) pp. 2379-2391. (2014)

Dozsa, A., Dezso, B., Toth, B.I., Bacsi, A., Poliska, S., Camera, E., Picardo, M., Zouboulis, C.C., Biro, T., Schmitz, G., Liebisch, G., Ruhl, R., Remenyik, E., Nagy, L.
PPARgamma-Mediated and Arachidonic Acid-Dependent Signaling is Involved in Differentiation and Lipid Production of Human Sebocytes.
Journal of Investigative Dermatology 134:(4) pp. 910-920. (2014)

2013

Brignull, L.M., Czimmerer, Z., Saidi, H., Daniel, B., Villela, I., Bartlett, N.W., Johnston, S.L., Meira, L.B., Nagy, L., Nohturfft, A.
Reprogramming of lysosomal gene expression by interleukin-4 and Stat6.
BMC Genomics 14: Paper 853. (2013)

Cuaranta-Monroy, I., Nagy, L.
PPARy needs a helping hand to make fat
Cell Death and Differentiation 20: pp. 1599-1600. (2013)

Czimmerer, Z., Hulvely, J., Simandi, Z., Varallyay, E., Havelda, Z., Szabo, E., Varga, A., Dezso, B., Balogh, M., Horvath, A., Domokos, B., Torok, Z., Nagy, L., Balint, B.L.
A versatile method to design stem-loop primer-based quantitative PCR assays for detecting small regulatory RNA molecules.
Plos One 8:(1) p. e55168. 1 p. (2013)

Gyongyosi, A., Szatmari, I., Pap, A., Dezso, B., Pos, Z., Szeles, L., Varga, T., Nagy, L.
RDH10, RALDH2 and CRABP2 are required components of PPARg-directed all-trans-retinoic acid synthesis and signaling in human dendritic cells
Journal of Lipid Research 54:(9) pp. 2458-2474. (2013)

Kiss, M., Czimmerer, Zs., Nagy, L.
The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function - from physiology to pathology
Journal of Allergy and Clinical Immunology 132:(2) pp. 264-286. (2013)

Mesko, B., Poliska, S., Váncsa, A., Szekanecz, Z., Palatka, K., Hollo, Z., Horvath, A., Steiner, L., Zahuczky, G., Podani, J., Nagy, L.
Peripheral blood derived gene panels predict response to infliximab in rheumatoid arthritis and Crohn’s disease
Genome Medicine: Medicine in the Post-Genomic Era 5: p. 1. (2013)

Nagy, G., Daniel, B., Jonas, D., Nagy, L., Barta, E.
A novel method to predict regulatory regionsbased on histone mark landscapes in macrophages
Immunobiology 218:(11) pp. 1416-1427. (2013)

Nagy Laszlo
Nuclear hormone receptors are powerful regulators of stem cell maintenance, differentiation, metabolism and function
Seminars in Cell and Developmental Biology 24:(10-12) p. 669. (2013)

Nagy, Z., Czimmerer, Z., Nagy, L.
Nuclear receptor mediated mechanisms of macrophage cholesterol metabolism
Molecular and Cellular Endocrinology 368:(1-2) pp. 85-98. (2013)

Nagy, Zs., Ross, J., Rodriguez, G., Balint, L. B., Szeles, L., Nagy, L., Kirken, R. A.
Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cells
Plos One 8:(2) p. &. (2013)

Nagy, Zs., Czimmerer, Zs,. Nagy, L.
Pro-inflammatory cytokines negatively regulate PPARg mediated gene expression in both human and murine macrophages via multiple mechanisms
Immunobiology 218:(11) pp. 1336-1344. (2013)

Simándi, Z., Cuaranta-Monroy, I., Nagy, L.
Nuclear receptors as regulators of stem cell and cancer stem cell metabolism
Seminars in Cell and Developmental Biology 24:(10-12) pp. 716-723. (2013)

Szekanecz, Z., Mesko, B., Poliska, S., Vancsa, A., Szamosi, S., Vegh, E., Simkovics, E., Laki, J., Kurko, J., Besenyei, T., Mikecz, K., Glant, T., Nagy, L.
Pharmacogenetics and pharmacogenomics in rheumatology
Journal of Immunological Research 56:(2-3) pp. 325-333. (2013)

Szenasi, T., Kenesi, E., Nagy, A., Molnar, A., Balint, B.L., Zvara, A., Csabai, Z., Deak, F., Boros Olah, B., Mates, L., Nagy, L., Puskas, L.G., Kiss, I.
Hmgb1 can facilitate activation of the matrilin-1 gene promoter by Sox9 and L-Sox5/Sox6 in early steps of chondrogenesis.
Biochimia et Biophysica Acta-gene Regulatory Mechanisms 1829:(10) pp. 1075-1091. (2013)

Varga, T., Mounier, R., Gogolak, P., Poliska, S., Chazaud, B., Nagy, L.
Tissue LyC6- macrophages are generated in the absence of circulating LyC6- monocytes and Nur77 in a model of muscle regeneration.
Journal of Immunology 191:(11) pp. 5695-5701. (2013)

2012

Czimmerer, Z., Varga, T., Poliska, S., Nemet, I., Szanto, A., Nagy, L.
Identification of novel markers of human alternative macrophage activation including potential endogenous PPARγ ligand production mechanisms
Immunobiology 217:(12) pp. 1301-1314. (2012)

Mesko, B., Poliska, S., Szamosi, S., Szekanecz, Z., Podani, J., Varadi, C., Guttman, A., Nagy, L.
Peripheral blood gene expression and IgG glycosylation profiles as markers of tocilizumab treatment in rheumatoid arthritis
Journal of Rheumatology 39:(5) pp. 916-928. (2012)

Mesko, B., Zahuczky, G., Nagy, L.
The triad of success in personalized medicine: pharmacogenomics, biotechnology and regulatory issues from a Central European perspective
New Biotechnology 29:(6) pp. 741-750. (2012)

Nagy, L., Szanto, A., Szatmari, I., Szeles, L.
Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response
Physiological Reviews 92:(2) pp. 739-789. (2012)

Nagy, L.
Would eating carotts protect your liver? A new role involving NKT cells for retinoic acid in hepatitis
European Journal of Immunology 42:(7) pp. 1677-1680. (2012)

Oros, M., Zavaczki, E., Vadasz, C., Jeney, V., Tosaki, A., Lekli, I., Balla, G., Nagy, L., Balla, J.
Ethanol increases phosphate-mediated mineralization and osteoblastic transformation of vascular smooth muscle cells
Journal of Cellular and Molecular Medicine 16:(9) pp. 2219-2226. (2012)

Poliska, S., Penyige, A., Lakatos, P.L., the Hungarian IBD Study Group, Papp, M., Palatka, K., Lakatos, L., Molnar, T., Nagy, L.
Egyéb szerzőség: Kiss LS (kollaborációs közrem.);
Association of Peroxisome Proliferator-activated Receptor Gamma Polymorphisms to Inflammatory Bowel Disease in a Hungarian cohort
Inflammatory Bowel Diseases 18:(3) pp. 472-479. (2012)

Tsakiris, I., Torocsik, D., Gyongyosi, A., Dozsa, A., Szatmari, I., Szanto, A., Soos, G., Nemes, Z., Igali, L., Marton, I., Takats, Z., Nagy, L., Dezso, B.
Carboxypeptidase-M is regulated by lipids and CSFs in macrophages and dendritic cells and expressed selectively in tissue granulomas and foam cells.
Laboratory Investigation 92:(3) pp. 345-361. (2012)